On April 15, 2022, John Ellis resigned from his position as Chief Accounting Officer of 2U, Inc. (the “Company”), effective April 30, 2022, to pursue other professional opportunities. Mr. Ellis's resignation was not the result of any disagreement with the Company on any matter relating to the Company's operations, policies or practices. Mr. Paul S. Lalljie, Chief Financial Officer, will assume the role of Principal Accounting Officer, effective upon Mr. Ellis's resignation.