The board 3SBio Inc. announced that due to the Company's new engagement at its discretion of an external corporate services firm to provide general corporate and secretarial support services to the Company for efficiency, on 21 January 2022, the Board has approved the proposed change of company secretary of the Company and the appointment of the proposed delegate from the new corporate services firm as the new Company Secretary. In light of the above, the delegate from the former external corporate services firm engaged by the Company, Mr. LEE Kwok Fai Kenneth ("Mr. Lee"), has resigned from his positions as the Company Secretary, the authorized representative of the Company (the "Authorized Representative") under Rule 3.05 of the Rules (the "Listing Rules") Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited (the "Stock Exchange") and the process agent for the acceptance of service of process and notices on behalf of the Company in Hong Kong under Part 16 of the Companies Ordinance (Chapter 622 of the Laws of Hong Kong) (the "Process Agent"), with effect from 10 February 2022. The Board is pleased to further announce that the delegate from the new corporate services firm, Ms. Lai Siu Kuen ("Ms. Lai"), has been appointed by the Company as the Company Secretary, the Authorized Representative and the Process Agent in place of Mr. Lee, with effect from 10 February 2022.

Ms. Lai had previously served as a joint company secretary of the Company since the date of listing of the Company on the Main Board of the Stock Exchange up to 20 August 2018 when she left the former corporate services firm. Ms. Lai is currently a director of Corporate Services of Tricor Services Limited. The Board announces that with effect from 21 January 2022, Dr. WONG Da Silva Lap Yan Leo De Rothschild (formerly known as Wong Lap Yan) ("Dr. Wong") has resigned as an independent non- executive Director, the chairman of the remuneration committee (the "Remuneration Committee") and a member of each of the audit committee (the "Audit Committee") and nomination committee (the "Nomination Committee") of the Company due to his decision to devote more time to his personal endeavours.

The Board further announces that with effect from 21 January 2022, Mr. NG, Joo Yeow Gerry ("Mr. Ng") has been appointed as an independent non-executive Director. Mr. NG, Joo Yeow Gerry, aged 57, has substantial experience in corporate planning, business expansion and development as well as cross-border management, particular in investment management business in the Asian region. Mr. Ng has been an Independent Non-executive Director of AIA Company (Trustee) Limited.

In light of the above change of independent non-executive Director, with effect from 21 January 2022, Ms. YANG, Hoi Ti Heidi has been appointed as the chairman of the Remuneration Committee and Mr. Ng has been appointed as a member of each of the Audit Committee and the Nomination Committee.