DiagnoCure Inc. Announces PROGENSA PCA3 Test Featured at American Urological Association Meeting
May 25, 2012 at 07:30 am EDT
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DiagnoCure Inc. reported that the PROGENSA PCA3 prostate cancer diagnostic test has been featured in a number of presentations and discussions at the American Urological Association (AUA) meeting in Atlanta, GA. The value of PCA3 testing was highlighted during a debate on the new USPSFT recommendation on prostate cancer screening. PCA3 testing was the topic of 14 presentations during the meeting. USPSTF Recommendation on Prostate Cancer Screening - Implications for PROGENSA PCA3 Test. DiagnoCure management believes that the USPSTF recommendation may have positive implications for the use of the PROGENSA PCA3 test. The PCA3 urine test provides an opportunity to reduce the harm of PSA screening by reducing the number of unnecessary biopsies while identifying the lethal cancers. Clinical Data on PROGENSA PCA3: A total of 880 eligible men were enrolled, including 305 who had a prior negative prostate biopsy. Men with a PCA3 score >60 had 80% probability of a positive biopsy while those with a PCA3 score <20 had 88% probability of having a negative biopsy. The results validated the initial hypothesis of the authors. PCA3 performance was superior to all other diagnostic tools tested in the study for the detection of any cancer and high grade cancers. The authors believe those results, which are significant improvements over classical diagnostic tools, will allow PCA3 to greatly enhance clinical decision making. The PROGENSA PCA3 assay was approved by the FDA on February 15 and is the first urine--based molecular test to help determine the need for repeat prostate biopsies in men who have had a previous negative biopsy. The test is marketed by Gen-Probe, DiagnoCure's commercial partner.
9342-8530 Quebec Inc is a Canada-based biotechnology company. The Company specializes in the development and commercialization of products relating to the diagnosis of cancer. It intends to focus its activities on business development efforts by out-licensing, selling, or partnering with third parties with regards to its Previstage GCC and its new multimarker prostate cancer test (PCP). The Company's colorectal cancer staging test, Previstage GCC, uses the Guanylyl Cyclase C (GCC or GUCY2C) marker to stratify the risk of colon cancer recurrence by determining the stage of the disease. Previstage GCC Colorectal Cancer Staging test is a molecular test for the staging of colorectal cancer patients. The PROGENSA PCA3 assay is a molecular urine test that can be used as a predictor of biopsy outcome in men with a serum prostate specific antigen (PSA) level over 2.5 nanograms per milliliter (ng/ml).