On August 20, 2021, Preetam Shah, the principal financial and accounting officer of Brainstorm Cell Therapeutics Inc. (the Company"), provided the Company with notice of his intent to resign from the Company, effective August 31, 2021. The Board of Directors of the Company has appointed Alla Patlis, the Company's current Controller, as the Company's principal financial officer and principal accounting officer, effective upon Mr. Shah's resignation if a permanent Chief Financial Officer is not appointed prior to that time. Ms. Patlis has served as the Company's Controller since December 2012. From May 2015 to July 2015 and November 2016 to November 2017, Ms. Patlis served as the Company's Interim Chief Financial Officer.