Chemesis International Inc. announced that the Department of Health of Puerto Rico ("Department of Health") has not renewed licenses held by GSRX Industries Inc. ("GSRX") which are necessary for the operation of its cannabis dispensaries in Puerto Rico, and that, as a result, GSRX's cannabis dispensaries are no longer operating. The Company is uncertain at this point as to whether or when such licenses will be renewed. At present, the operations of the Company's subsidiary, Natural Ventures PR, LLC, are continuing in the ordinary course. The Company notes, further to its news release dated September 28, 2020, that the Department of Health is engaged in a review of certain filings made by the Company's subsidiary, GSRX Industries Inc. ("GSRX") with the Department of Health, which such review is in addition to the ongoing administrative review by the Department of Health previously announced by the Company.