Artemis Therapeutics Inc. announced that it has entered into a material definitive agreement to issue two unsecured promissory notes in the aggregate principal amount of $60,000 on November 4, 2021. The original issuance dates of notes are September 19, 2021 and August 15, 2021. One Note, with a principal aggregate balance of $30,000, was issued to KNRY Ltd., an entity related to Nadav Kidron, the natural person with voting and dispositive power over the securities held by Tonak Ltd., the company's largest shareholder.

One note, with an aggregate principal balance of $30,000, was issued to Harmony (H.A.) Investments Ltd. Each note accrues interest at a rate of 10% per annum until the note is repaid in full. All payments of principal, interest and other amounts under each note are payable by December 19, 2021.