OXFORD BIODYNAMICS PLC
This event, hosted by GenomeWeb and PMLS, will be an exceptional opportunity to present the unique benefit of EpiSwitch CiRT to accurately predict a cancer patient's most likely response to ICI therapy with a simple blood sample through liquid biopsy. Building on his personal experience,
The event is regularly attended by renowned oncologists, pathologists, clinical lab managers, executives, pharmaceutical and biotech R&D professionals, and decision-makers at hospitals and healthcare systems.
Liquid biopsies, a key focus topic for this year's event, offer several advantages over traditional tissue-based testing due to their non-invasive nature, avoiding a needle biopsy or surgical sampling, and capacity to allow continuous patient monitoring. OBD is the commercial pioneer and technological leader in isolating and analyzing 3D genomic biomarkers from a simple blood draw to guide treatment decisions, assess prognosis, and predict therapy response. In addition, the EpiSwitch platform allows researchers to comprehensively examine complex system-wide regulatory interactions between the host immune system and cancer to detect early cancer, predict its response to drugs, and even stratify patients to likely outcomes.
Contact:
Tel: +44 (0)1865 518910
About
Its flagship product is EpiSwitch CiRT (Checkpoint Inhibitor Response Test) for cancer, a predictive immune response profile for immuno-oncology (IO) checkpoint inhibitor treatments, launched in
In
The Company has developed a proprietary 3D genomic biomarker platform, EpiSwitch, which can build molecular diagnostic classifiers for prediction of response to therapy, patient prognosis, disease diagnosis and subtyping, and residual disease monitoring in a wide range of indications.
Oxford BioDynamics has participated in more than 40 partnerships with big pharma and leading institutions including
The Company has created a valuable technology portfolio, including biomarker arrays, molecular diagnostic tests, bioinformatic tools for 3D genomics and an expertly curated 3D genome knowledgebase comprising hundreds of millions of data points from over 10,000 samples in more than 30 human diseases.
OBD is headquartered in
About EpiSwitch
The 3D configuration of the genome plays a crucial role in gene regulation. By mapping this architecture and identifying abnormal configurations, EpiSwitch can be used to diagnose patients or determine how individuals might respond to a disease or treatment.
Built on over 10 years of research, EpiSwitch is Oxford Biodynamics' award-winning, proprietary platform that enables screening, evaluation, validation and monitoring of 3D genomic biomarkers. The technology is fully developed, based on testing of over 10,000 samples in 30 disease areas, and reduced to practice.
In addition to stratifying patients with respect to anticipated clinical outcome, EpiSwitch data offer insights into systems biology and the physiological manifestation of disease that are beyond the scope of other molecular modalities. The technology has performed well in academic medical research settings and has been validated through its integration in biomarker discovery and clinical development with big pharma.
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