On February 23, 2018, Michael P. Miller was appointed to the Board of Directors of Puma Biotechnology, Inc. Mr. Miller will serve on the Board for a term expiring at the 2018 Annual Meeting of Stockholders and until his successor is duly elected and qualified, or until his earlier death, resignation or removal. Mr. Miller has served as the Executive Vice President U.S. Commercial of Jazz Pharmaceuticals plc, since May 2017 and as its Senior Vice President U.S. Commercial from April 2014 until May 2017.