On March 14, 2022, Mr. James C. D'Arecca, principal financial officer of TherapeuticsMD, Inc., notified the company of his decision to resign from such position, effective as of April 1, 2022. Mr. Michael C. Donegan, the Vice President – Finance and Chief Accounting Officer of the company, will succeed Mr. D'Arecca as principal financial and accounting officer as of the effective date of Mr. D'Arecca's resignation.