UCB A total of 17 abstracts, including an oral presentation, will feature data from studies of four approved and one investigational medicine and technologies for generalized myasthenia gravis (gMG), epilepsies including Dravet syndrome and focal (partial) epileptic seizures.
Key UCB scientific and patient-focused data to be presented at AAN include: gMG
Post hoc and open-label extension analyses from the pivotal Phase 3 MycarinG study for rozanolixizumab, including impact of treatment on physical fatigue and muscle fatigability in adult patients with gMG
An oral presentation on long-term safety and efficacy of zilucoplan in gMG in an interim analysis of RAISE-XT
An interim analysis of a Phase 3b study on efficacy, and patient preference for subcutaneous zilucoplan in Myasthenia Gravis after switching from intravenous complement component 5 inhibitors
Results from a discrete choice study looking at patient preferences in gMG treatment attributes
Epilepsy and rare epilepsy syndromes
Focal-onset seizures (FOS) - interim results of 12-month real-world study (BRITOBA) evaluating adjunctive brivaracetam in earlier treatment lines in adults
Epilepsy - subgroup data from the international EXPERIENCE analysis assessing brivaracetam in epilepsy patients with cognitive or learning disability or psychiatric comorbidities
Prolonged seizures - three Phase 1 studies evaluating the safety, tolerability, and pharmacokinetics of single-use inhaled alprazolam (an investigational treatment for potential termination of prolonged epileptic seizures) in different populations
Dravet syndrome - a retrospective analysis using US claims data of healthcare utilization and persistence in patients with Dravet syndrome
Epilepsy disease management - expert consensus recommendations from the
'The new analyses from the Phase 3 MycarinG and Phase 3 RAISE XT open-label extension (OLE) studies being presented at this year's AAN meeting reinforce the potential of our recently approved gMG treatments, RYSTIGGO and ZILBRYSQ, to offer targeted treatments for adult gMG patients, tailored to their individual needs and preferences,' commented
'For people living with epilepsy and rare epilepsy syndromes, the data being presented at this year's AAN meeting showcase how we are transforming experiences and outcomes and redefining the future of epilepsy care,' said
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