Virtus Total Return Fund Inc. Announces Monthly Distribution, Payable on May 20, 2021

Virtus Total Return Fund Inc. (the Fund) is a closed-end, diversified management investment company. The Fund's investment objective is capital appreciation, with current income as a secondary objective. The Fund invests approximately 60% of its total assets in equity securities, managed by Duff & Phelps Investment Management Co. The Fund invests 40% in fixed income, managed by Newfleet Asset Management, LLC. Its products include mutual funds, retail separate accounts, closed-end funds, variable insurance funds, exchange-traded funds (ETFs), undertakings for the collective investment in transferable securities (UCITS) and CollegeAccess 529. The Fund invests in consumer discretionary, financials, healthcare, industrials, consumer staples, telecommunication services, energy, information technology, materials and utility sectors. The Fund's investment adviser is Virtus Investment Advisers, Inc.