On June 5, 2019, Luke Düster notified Zyla Life Sciences of his resignation from the Board of Directors of the Company. Mr. Düster's resignation is expressly conditioned upon the Board's election of Gary M. Phillips, M.D. to fill the resulting vacancy. On June 5, 2019, the Iroko Stockholders notified the Board of their nomination of Dr. Phillips to fill that vacancy and serve as a director of the Company. The Board will consider Dr. Phillips' nomination in accordance with the Company's governance policies and obligations under the Stockholders' Agreement.