China Resources Pharmaceutical Group Limited and China Resources Medical Holdings Company Limited dated September 17, 2020 in relation to the Cooperation Framework Agreement 2020. As the Cooperation Framework Agreement 2020 and the annual caps thereunder shall expire on December 31, 2022 and cease to have effect on January 1, 2023, CR Pharmaceutical and CR Medical entered into the Cooperation Framework Agreement 2023/2024 on 29 December, 2022 for a term of two years commencing from January 1, 2023, pursuant to which CR Medical Group shall provide CR Pharmaceutical Group with Supply Chain Management Services of medical supplies in order to improve the efficiency of supply chain management of CR Pharmaceutical Group's medical supplies and reduce the corresponding costs. CR Medical Group shall receive management service fees from CR Pharmaceutical Group for the abovementioned services.

Scope of the Supply Chain Management Services: CR Medical Group shall provide CR Pharmaceutical Group with Supply Chain Management Services of medical supplies which include establishing regional supply chain management platforms in specific regions and streamlining supply chain management procedures, based on the conditions of management, business operation and other relevant factors of CR Pharmaceutical Group. Through systems integration, the Supply Chain Management Services shall optimise the mechanism and enhance the process of supply chain management of medical supplies in order to assist CR Pharmaceutical Group in improving efficiency and reducing the costs. Pricing Basis and Pricing Policies: CR Pharmaceutical Group shall pay management service fees to CR Medical Group for the provision of Supply Chain Management Services.

The relevant fee is calculated by multiplying the management service fee rate by the scale of Supply Chain Management Services provided to CR Pharmaceutical Group in specific regions within a specified period of time or in a specific scope. The Parties shall determine the abovementioned scale of Supply Chain Management Services based on the following factors including (1) the specific cooperation regions or the scope of specific medical institutes; (2) the expected volume of the corresponding annual supply of medical supplies; and (3) the nature of the geographic area where specific management services are provided. In respect of the management service fee rates for the Supply Chain Management Services, the Parties shall determine specific fee rates via arm's length negotiation between the Parties and on normal commercial terms and with reference to management service fee rates provided to third-party clients of CR Medical Group under similar service scope, service types and conditions, and the specifications of expected medical supplies and the number of brands involved, the expected medical material supply management complexity and the expected quality of the management services (i.e. the expected results of supply management services including timely arrival rate, quality pass rate and cost control effect, etc.).

Separate agreements will be entered into by the Parties in respect of specific Supply Chain Management Services pursuant to the Cooperation Framework Agreement 2023/2024, in which management service fee rates shall be determined on a case-by-case basis taking into account the factors mentioned above. The corresponding payment terms shall also be separately agreed in accordance with the principles laid down in the Cooperation Framework Agreement 2023/2024.