InMed Pharmaceuticals Inc. announced that an abstract describing the Phase 2 clinical study of investigational drug INM-755 Cannol ("CBN") cream for the treatment of symptoms in patients with epidermolysis bullosa ("EB"), a rare genetic skin disease, has been accepted as an oral presentation at the 12th World Congress on Itch (WCI), being held in Miami on November 5-7, 2023. The Phase 2 study was designed to evaluate the safety of INM-755 CBN cream, which consists of the control cream plus the active pharmaceutical ingredient CBN, and obtain preliminary evidence of efficacy in treating symptoms and healing wounds over a 28-day period in patients with EB. All four subtypes of inherited EB, including EB Simplex, Dystrophic EB, Junctional EB, and Kindler Syndrome were accepted into the study.

The study used a within-patient, double-blind design whereby matched index areas were randomized to INM-755 CBN Cream or to control cream. The data showed a positive indication of enhanced anti-itch activity for INM-755 Cannol cream versus the control cream alone.