Nuo Therapeutics, Inc. entered into a securities purchase agreement with certain accredited investors for issuance of 1,925,000 common shares at a price of $0.50 per share for gross proceeds of $962,500 on December 8, 2023. The investors Scott M. Pittman for $300,000 for 600,000 shares of Common Stock, Peter A. Clausen for $10,000 for 20,000 shares and Charles E. Sheedy for $75,000 for 150,000 shares. The company issued securities subject to the terms and conditions set forth in this Agreement and pursuant to Section 4(a)(2) of the Securities Act of 1933, as amended and Rule 506 of Regulation D promulgated thereunder.