PharmaEngine, Inc. announced the following changes to the board: Name of the previous position holder: Tu, Ted. Resume of the previous position holder: Chairman of PharmaEngine Inc. Name of the new position holder: Hsu, Jan-Yau .Resume of the new position holder: Former Chairman of TWSE. Reason for the change: TTY Biopharm Company Limited assigned a new representative to serve as institutional director.

Effective date of the new appointment is September 1, 2022.