Pioneer Municipal High Income Advantage Trust Declares Monthly Distribution for the Month of September 2020, Payable on September 30, 2020

Pioneer Municipal High Income Advantage Fund, Inc. (the Fund) is a diversified closed-end management investment company. The investment objective of the Fund is to seek a high level of current income exempt from regular federal income tax, and the Fund may, as a secondary objective, also seek capital appreciation to the extent that it is consistent with its primary investment objective. Under normal market conditions, the Fund invest substantially all (at least 80%) of its assets in debt securities. The Fund may invest in municipal securities with a broad range of maturities and credit ratings, including both investment grade and below investment grade municipal securities. The investment adviser of the Fund is Amundi Asset Management US, Inc.