As previously reported, on March 31, 2022, United Therapeutics Corporation entered into a Credit Agreement (the Credit Agreement) with certain of its subsidiaries party thereto, as guarantors, the lenders referred to therein, and Wells Fargo Bank, National Association (Wells Fargo), as administrative agent and as a swingline lender. The Credit Agreement provides for (i) an unsecured revolving credit facility of up to $1.2 billion; and (ii) a second unsecured revolving credit facility of up to $800 million (which facilities may, subject to obtaining commitments from existing or new lenders for such increase and subject to other conditions, be increased by up to $500 million in the aggregate). The facilities mature five years after the closing date of the Credit Agreement, subject to an ability of the lenders thereunder, or certain of the lenders thereunder, to elect to extend the maturity date of their commitments by one year following a request for such extension by the Company in accordance with the terms of the Credit Agreement, up to a maximum of two such extensions.

As previously reported, on March 31, 2023, the Company exercised its first one-year extension option, extending the maturity of the commitments and loans of each lender under the Credit Agreement by one year to March 31, 2028. Pursuant to Section 2.7 of the Credit Agreement, the maturity of the commitments and loans of each lender under the Credit Agreement has been extended by one additional year to March 31, 2029. The maturity extension became effective as of March 29, 2024.