Notification as owner of a substantial interest according to section 27a para 1 of the German Securities Trading Act (Wertpapierhandelsgesetz - WpHG), , We have informed you according to section 21, 22 WpHG together with our telefax dated 7 April 2017 that our voting interest in RHÖN-KLINIKUM Aktiengesellschaft has crossed the 25 percent threshold by 6 April 2017.

With respect to the objectives pursued with the acquisition of the voting rights, Prof. Dr. h.c. Ludwig Georg Braun, Ilona Braun, Martin Lüdicke, B. Braun Holding GmbH & Co. KG, BraHo Verwaltungsgesellschaft mbH, Ludwig G. Braun GmbH & Co. KG and B. Braun Melsungen Aktiengesellschaft have informed us pursuant to section 27a para 1 sentence 1, 3 WpHG of the following:

1. We consider our shareholding in RHÖN-KLINIKUM Aktiengesellschaft as a long-term strategic investment.

2. Our thoughts about acquiring further voting rights within the upcoming 12 months have not yet been finalized.

3. We are seeking a permanent representation in the supervisory board of RHÖN-KLINIKUM Aktiengesellschaft correlating to our respective shareholding in RHÖN-KLINIKUM Aktiengesellschaft. Beyond that an exertion on influence on the composition of the administration, management or supervisory boards of RHÖN-KLINIKUM Aktiengesellschaft is not intended.

4. We are not seeking an essential change of the capital structure of RHÖN-KLINIKUM Aktiengesellschaft, especially with regard to the ratio of internal/outside financing and dividend policy.

We are disclosing according to section 27a para 1 sentence 4 WpHG regarding the origin of the medium used for acquisition that we partly used own funds, but predominantly external funds, which were raised to finance the acquisition of the voting rights.

Bad Neustadt a. d. Saale, 9 May 2017

Dr. Kai G. Klinger, SVP - Investor Relations, Corporate Finance and M&A, RHÖN-KLINIKUM AG, Schlossplatz 1, 97616 Bad Neustadt a. d. Saale, Phone: +49 9771 65 - 1318, FAX: +49 9771 99 - 1736

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